Pauses During Autobiographical Discourse Reflect Episodic Memory Processes in Early Alzheimer's Disease.

ABSTRACT: There is a large body of research on discourse production in Alzheimer's disease (AD). Some studies have focused on pause production, revealing that patients make extensive use of pauses during speech. This has been attributed to lexical retrieval difficulties, but pausing may also reflect other forms of cognitive impairment as it increases with cognitive load. The aim of the present study was to analyze autobiographical discourse impairment in AD from a broad perspective, looking at pausing behavior (frequency, duration, and location). Our first objective was to characterize discourse changes in mild cognitive impairment (MCI) due to AD. Our second objective was to determine the cognitive and neuroanatomical correlates of these changes. Fifteen patients with MCI due to AD and 15 matched c

SUBMITTER: Pistono A 

PROVIDER: S-EPMC4927846 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature