Tracking Parkinson's: Study Design and Baseline Patient Data.

ABSTRACT:

Background

There is wide variation in the phenotypic expression of Parkinson's disease (PD), which is driven by both genetic and epidemiological influences.

Objectives

To define and explain variation in the clinical phenotype of PD, in relation to genotypic variation.

Methods

Tracking Parkinson's is a multicentre prospective longitudinal epidemiologic and biomarker study of PD. Patients attending specialist clinics in the United Kingdom with recent onset (<3.5 years) and young onset (diagnosed <50 years of age) PD were enrolled. Motor, non-motor and quality of life assessments were performed using validated scales. Cases are followed up 6 monthly up to 4.5 years for recent onset PD, and up to 1 year for young onset PD. We present here baseline clinical data from this

SUBMITTER: Malek N 

PROVIDER: S-EPMC4927877 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature