The rat suprachiasmatic nucleus: the master clock ticks at 30 Hz.

ABSTRACT:

Key points

Light-responsive neurones in the rat suprachiasmatic nucleus discharge with a harmonic distribution of interspike intervals, whereas unresponsive neurones seldom do. This harmonic patterning has a fundamental frequency of close to 30 Hz, and is the same in light-on cells as in light-off cells, and is unaffected by exposure to light. Light-on cells are more active than light-off cells in both subjective day and subjective night, and both light-on cells and light-off cells respond more strongly to changes in light intensity during the subjective night than during the subjective day. Paired recordings indicate that the discharge of adjacent light-responsive cells is very tightly synchronized. The gap junction inhibitor carbenoxolone increases the spontaneous activity of sup

SUBMITTER: Tsuji T 

PROVIDER: S-EPMC4929337 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature