The more the merrier? How a few SNPs predict pigmentation phenotypes in the Northern German population.

ABSTRACT: Human pigmentation traits are of great interest to many research areas, from ancient DNA analysis to forensic science. We developed a gene-based predictive model for pigmentation phenotypes in a realistic target population for forensic case work from Northern Germany and compared our model with those brought forth by previous studies of genetically more heterogeneous populations. In doing so, we aimed at answering the following research questions: (1) do existing models allow good prediction of high-quality phenotypes in a genetically similar albeit more homogeneous population? (2) Would a model specifically set up for the more homogeneous population perform notably better than existing models? (3) Can the number of markers included in existing models be reduced without compromising their

SUBMITTER: Caliebe A 

PROVIDER: S-EPMC4930077 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature