Parenthood and the risk of diabetes in men and women: a 7 year prospective study of 0.5 million individuals.

ABSTRACT:

Aims/hypothesis

In women, higher parity has been associated with increased risk of diabetes later in life. It is unclear, however, whether this association is mainly due to biological effects of childbearing, or to socioeconomic and lifestyle factors associated with childrearing. We assessed the association between number of children and diabetes risk separately in women and men.

Methods

Between 2004 and 2008, the nationwide China Kadoorie Biobank recruited 0.5 million individuals aged 30-79 (mean 51 years) from ten diverse regions across China. During 7 years of follow-up, 8,840 incident cases of diabetes were recorded among 463,347 participants without prior cardiovascular diseases or diabetes. Multivariable Cox regression yielded sex-specific HRs and 95% CIs for incident

SUBMITTER: Peters SA 

PROVIDER: S-EPMC4930461 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature