Is oocyte donation a risk factor for preeclampsia? A systematic review and meta-analysis.

ABSTRACT:

Purpose

The objective of this meta-analysis is to determine whether there is a higher incidence of preeclampsia (PE) in pregnancies achieved by oocyte donation (OD) compared with pregnancies achieved by in vitro fertilization with autologous oocytes (IVF).

Methods

A systematic review was performed to identify relevant studies published from January 1994 until April 2015 with at least an abstract in English using PubMed, ISI Web of Knowledge, and clinicaltrials.gov. The 11 studies included in this systematic review were retrospective and prospective cohort studies of women reporting results on the association between oocyte donation vs. in vitro fertilization (exposure) and preeclampsia (outcome).

Results

Oocyte donation is a risk factor for the development of PE compa

SUBMITTER: Blazquez A 

PROVIDER: S-EPMC4930777 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature