The association between multinucleated blastomeres and poor ovarian response under the Bologna criteria.

ABSTRACT:

Purpose

To investigate the occurrence of multinucleated blastomeres (MNB) in poor ovarian response (POR) women defined under the Bologna criteria.

Methods

This observational study was designed in a prospective controlled manner. Among 380 cases evaluated for eligibility, 102 women were found suitable and recruited; 51 with POR in accordance with the Bologna criteria defined as the study group and 51 with normal ovarian response defined as the control group.

Results

Among the 51 women in each group, 8 and 2 did not achieve embryos in the study and control group, respectively (P < 0.05). The percentage of women that had at least one embryo with one MNB was significantly higher in the study as compared to the control group, corresponding to 49 and 29 %, respectively. The

SUBMITTER: Younis JS 

PROVIDER: S-EPMC4930787 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature