A Combinatorial Algorithm for Microbial Consortia Synthetic Design.

ABSTRACT: Synthetic biology has boomed since the early 2000s when it started being shown that it was possible to efficiently synthetize compounds of interest in a much more rapid and effective way by using other organisms than those naturally producing them. However, to thus engineer a single organism, often a microbe, to optimise one or a collection of metabolic tasks may lead to difficulties when attempting to obtain a production system that is efficient, or to avoid toxic effects for the recruited microorganism. The idea of using instead a microbial consortium has thus started being developed in the last decade. This was motivated by the fact that such consortia may perform more complicated functions than could single populations and be more robust to environmental fluctuations. Success is howeve

SUBMITTER: Julien-Laferriere A 

PROVIDER: S-EPMC4931573 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature