Trajectories of adolescent conduct problems in relation to cortical thickness development: a longitudinal MRI study.

ABSTRACT: Multiple cross-sectional imaging studies have identified structural abnormalities in prefrontal, temporal and limbic regions related to conduct problems (CPs). However, the relationship between development of such neurobiological deficits and developmental pathways of CPs has remained unclear. The current study investigated distinct trajectories of CP and related trajectories of cortical thickness within a community-based sample of adolescents (n=239), age range 12-19, to address this gap. Three trajectory classes were revealed using latent class growth analyses (LCGAs), comprising a 'desisting' CP group, an 'intermediate' CP group and a 'stable low' CP group. Structural magnetic resonance imaging (MRI) scans were collected with a subgroup of 171 adolescents at three waves throughout adole

SUBMITTER: Oostermeijer S 

PROVIDER: S-EPMC4931609 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature