Lipid-Based Drug Delivery Systems in Cancer Therapy: What Is Available and What Is Yet to Come.

ABSTRACT: Cancer is a leading cause of death in many countries around the world. However, the efficacy of current standard treatments for a variety of cancers is suboptimal. First, most cancer treatments lack specificity, meaning that these treatments affect both cancer cells and their normal counterparts. Second, many anticancer agents are highly toxic, and thus, limit their use in treatment. Third, a number of cytotoxic chemotherapeutics are highly hydrophobic, which limits their utility in cancer therapy. Finally, many chemotherapeutic agents exhibit short half-lives that curtail their efficacy. As a result of these deficiencies, many current treatments lead to side effects, noncompliance, and patient inconvenience due to difficulties in administration. However, the application of nanotechnology

SUBMITTER: Yingchoncharoen P 

PROVIDER: S-EPMC4931871 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature