Sex hormones in women with and without migraine: Evidence of migraine-specific hormone profiles.

ABSTRACT:

Objective

To compare daily sex hormone levels and rates of change between women with history of migraine and controls.

Methods

History of migraine, daily headache diaries, and daily hormone data were collected in ovulatory cycles of pre- and early perimenopausal women in the Study of Women's Health Across the Nation. Peak hormone levels, average daily levels, and within-woman day-to-day rates of decline over the 5 days following each hormone peak were calculated in ovulatory cycles for conjugated urinary estrogens (E1c), pregnanediol-3-glucuronide, luteinizing hormone, and follicle-stimulating hormone. Comparisons were made between migraineurs and controls using 2-sample t tests on the log scale with results reported as geometric means.

Results

The sample included 114

SUBMITTER: Pavlovic JM 

PROVIDER: S-EPMC4932235 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature