The emergence and outbreak of multidrug-resistant typhoid fever in China.

ABSTRACT: Typhoid fever remains a severe public health problem in developing countries. The emergence of resistant typhoid, particularly multidrug-resistant typhoid infections, highlights the necessity of monitoring the resistance characteristics of this invasive pathogen. In this study, we report a typhoid fever outbreak caused by multidrug-resistant Salmonella enterica serovar Typhi strains with an ACSSxtT pattern. Resistance genes conferring these phenotypes were harbored by a large conjugative plasmid, which increases the threat of Salmonella Typhi and thus requires close surveillance for dissemination of strains containing such genes.

SUBMITTER: Yan M 

PROVIDER: S-EPMC4932652 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature