Discovery of new cellulases from the metagenome by a metagenomics-guided strategy.

ABSTRACT:

Background

Energy shortage has become a global problem. Production of biofuels from renewable biomass resources is an inevitable trend of sustainable development. Cellulose is the most abundant and renewable resource in nature. Lack of new cellulases with unique properties has become the bottleneck of the efficient utilization of cellulose. Environmental metagenomes are regarded as huge reservoirs for a variety of cellulases. However, new cellulases cannot be obtained easily by functional screening of metagenomic libraries.

Results

In this work, a metagenomics-guided strategy for obtaining new cellulases from the metagenome was proposed. Metagenomic sequences of DNA extracted from the anaerobic beer lees converting consortium enriched at thermophilic conditions were assemble

SUBMITTER: Yang C 

PROVIDER: S-EPMC4932676 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature