The Cell Ontology 2016: enhanced content, modularization, and ontology interoperability.

ABSTRACT:

Background

The Cell Ontology (CL) is an OBO Foundry candidate ontology covering the domain of canonical, natural biological cell types. Since its inception in 2005, the CL has undergone multiple rounds of revision and expansion, most notably in its representation of hematopoietic cells. For in vivo cells, the CL focuses on vertebrates but provides general classes that can be used for other metazoans, which can be subtyped in species-specific ontologies.

Construction and content

Recent work on the CL has focused on extending the representation of various cell types, and developing new modules in the CL itself, and in related ontologies in coordination with the CL. For example, the Kidney and Urinary Pathway Ontology was used as a template to populate the CL with additional ce

SUBMITTER: Diehl AD 

PROVIDER: S-EPMC4932724 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature