Mechanical thrombectomy in patients with acute ischemic stroke: a cost-utility analysis.

ABSTRACT:

Background

The beneficial effects of endovascular treatment with new-generation mechanical thrombectomy devices compared with intravenous thrombolysis alone to treat acute large-artery ischemic stroke have been shown in randomized controlled trials (RCTs). This study aimed to estimate the cost utility of mechanical thrombectomy compared with the established standard of care.

Methods

We developed a Markov decision process analytic model to assess the cost-effectiveness of treatment with mechanical thrombectomy plus intravenous thrombolysis versus treatment with intravenous thrombolysis alone from the public payer perspective in Canada. We conducted comprehensive literature searches to populate model inputs. We estimated the efficacy of mechanical thrombectomy plus intravenous

SUBMITTER: Xie X 

PROVIDER: S-EPMC4933608 | biostudies-literature | 2016 Apr-Jun

REPOSITORIES: biostudies-literature