Prevalence of human norovirus and Clostridium difficile coinfections in adult hospitalized patients.

ABSTRACT:

Objective

Human norovirus (HuNoV) and Clostridium difficile are common causes of infectious gastroenteritis in adults in the US. However, limited information is available regarding HuNoV and C. difficile coinfections. Our study was designed to evaluate the prevalence of HuNoV and C. difficile coinfections among adult patients in a hospital setting and disease symptomatology.

Study design and setting

For a cross-sectional analysis, 384 fecal samples were tested for the presence of C. difficile toxins from patients (n=290), whom the provider suspected of C. difficile infections. Subsequent testing was then performed for HuNoV genogroups I and II. Multinomial logistic regression was performed to determine symptoms more frequently associated with coinfections.

Results

The

SUBMITTER: Stokely JN 

PROVIDER: S-EPMC4934455 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature