Risk factors for subsequent febrile seizures in the FEBSTAT study.

ABSTRACT:

Objectives

To identify risk and risk factors for developing a subsequent febrile seizure (FS) in children with a first febrile status epilepticus (FSE) compared to a first simple febrile seizure (SFS). To identify home use of rescue medications for subsequent FS.

Methods

Cases included a first FS that was FSE drawn from FEBSTAT and Columbia cohorts. Controls were a first SFS. Cases and controls were classified according to established FEBSTAT protocols. Cumulative risk for subsequent FS over a 5-year period was compared in FSE versus SFS, and Cox proportional hazards regression was conducted. Separate analysis examined subsequent FS within FSE. The use of rescue medications at home was assessed for subsequent FS.

Results

Risk for a subsequent FSE was significantly inc

SUBMITTER: Hesdorffer DC 

PROVIDER: S-EPMC4935556 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature