Maximising HIV prevention by balancing the opportunities of today with the promises of tomorrow: a modelling study.

ABSTRACT:

Background

Many ways of preventing HIV infection have been proposed and more are being developed. We sought to construct a strategic approach to HIV prevention that would use limited resources to achieve the greatest possible prevention impact through the use of interventions available today and in the coming years.

Methods

We developed a deterministic compartmental model of heterosexual HIV transmission in South Africa and formed assumptions about the costs and effects of a range of interventions, encompassing the further scale-up of existing interventions (promoting condom use, male circumcision, early antiretroviral therapy [ART] initiation for all [including increased HIV testing and counselling activities], and oral pre-exposure prophylaxis [PrEP]), the introduction of

SUBMITTER: Smith JA 

PROVIDER: S-EPMC4935669 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature