In Vivo Investigation of the Effectiveness of a Hyper-viscoelastic Model in Simulating Brain Retraction.

ABSTRACT: Intraoperative brain retraction leads to a misalignment between the intraoperative positions of the brain structures and their previous positions, as determined from preoperative images. In vitro swine brain sample uniaxial tests showed that the mechanical response of brain tissue to compression and extension could be described by the hyper-viscoelasticity theory. The brain retraction caused by the mechanical process is a combination of brain tissue compression and extension. In this paper, we first constructed a hyper-viscoelastic framework based on the extended finite element method (XFEM) to simulate intraoperative brain retraction. To explore its effectiveness, we then applied this framework to an in vivo brain retraction simulation. The simulation strictly followed the clinical scenar

SUBMITTER: Li P 

PROVIDER: S-EPMC4937391 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature