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Detection of Rare Antimicrobial Resistance Profiles by Active and Passive Surveillance Approaches.


ABSTRACT: Antimicrobial resistance (AMR) surveillance systems are generally not specifically designed to detect emerging resistances and usually focus primarily on resistance to individual drugs. Evaluating the diversity of resistance, using ecological metrics, allows the assessment of sampling protocols with regard to the detection of rare phenotypes, comprising combinations of resistances. Surveillance data of phenotypic AMR of Canadian poultry Salmonella Heidelberg and swine Salmonella Typhimurium var. 5- were used to contrast active (representative isolates derived from healthy animals) and passive (diagnostic isolates) surveillance and assess their suitability for detecting emerging resistance patterns. Although in both datasets the prevalences of resistance to individual antimicrobials were no

SUBMITTER: Mather AE 

PROVIDER: S-EPMC4938605 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature