Ontology highlight
ABSTRACT:
SUBMITTER: Higashide M
PROVIDER: S-EPMC4938656 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Higashide Mika M Shinohara Miki M
G3 (Bethesda, Md.) 20160707 7
The number and distribution of meiosis crossover (CO) events on each bivalent are strictly controlled by multiple mechanisms to assure proper chromosome segregation during the first meiotic division. In Saccharomyces cerevisiae, Slx4 is a multi-functional scaffold protein for structure-selective endonucleases, such as Slx1 and Rad1 (which are involved in DNA damage repair), and is also a negative regulator of the Rad9-dependent signaling pathway with Rtt107 Slx4 has been believed to play only a ...[more]