Prior cancer does not adversely affect survival in locally advanced lung cancer: A national SEER-medicare analysis.

ABSTRACT:

Introduction

Management of locally advanced non-small cell lung cancer is among the most highly contested areas in thoracic oncology. In this population, a history of prior cancer frequently results in exclusion from clinical trials and may influence therapeutic decisions. We therefore determined prevalence and prognostic impact of prior cancer among these patients.

Materials and methods

We identified patients>65years of age diagnosed 1992-2009 with locally advanced lung cancer in the Surveillance, Epidemiology, and End Results-Medicare linked dataset. We characterized prior cancer by prevalence, type, stage, and timing. We compared all-cause and lung cancer-specific survival between patients with and without prior cancer using propensity score-adjusted Cox regression.

Re

SUBMITTER: Laccetti AL 

PROVIDER: S-EPMC4939247 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature