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Characterization of New Ent-kaurane Diterpenoids of Yunnan Arabica Coffee Beans.


ABSTRACT: Five new ent-kaurane diterpenoids, named mascaroside III-V (1-3), and 20-nor-cofaryloside I-II (4-5), together with seven known diterpenoids, were isolated from methanol extracts of the green coffee beans of Yunnan Arabica Coffee. Their chemical structures were elucidated by extensive spectroscopic analyses. Meanwhile, cytotoxicity assay against HL-60, A-549, SMMC-7721, MCF-7 and SW480 cell lines showed that they have not evident inhibition of cytotoxicity.

SUBMITTER: Chu R 

PROVIDER: S-EPMC4940257 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature

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Characterization of New Ent-kaurane Diterpenoids of Yunnan Arabica Coffee Beans.

Chu Rui R   Wan Luo-Sheng LS   Peng Xing-Rong XR   Yu Mu-Yuan MY   Zhang Zhi-Run ZR   Zhou Lin L   Li Zhong-Rong ZR   Qiu Ming-Hua MH  

Natural products and bioprospecting 20160510 4


Five new ent-kaurane diterpenoids, named mascaroside III-V (1-3), and 20-nor-cofaryloside I-II (4-5), together with seven known diterpenoids, were isolated from methanol extracts of the green coffee beans of Yunnan Arabica Coffee. Their chemical structures were elucidated by extensive spectroscopic analyses. Meanwhile, cytotoxicity assay against HL-60, A-549, SMMC-7721, MCF-7 and SW480 cell lines showed that they have not evident inhibition of cytotoxicity. ...[more]

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