COMODI: an ontology to characterise differences in versions of computational models in biology.

ABSTRACT:

Background

Open model repositories provide ready-to-reuse computational models of biological systems. Models within those repositories evolve over time, leading to different model versions. Taken together, the underlying changes reflect a model's provenance and thus can give valuable insights into the studied biology. Currently, however, changes cannot be semantically interpreted. To improve this situation, we developed an ontology of terms describing changes in models. The ontology can be used by scientists and within software to characterise model updates at the level of single changes. When studying or reusing a model, these annotations help with determining the relevance of a change in a given context.

Methods

We manually studied changes in selected models from BioModels

SUBMITTER: Scharm M 

PROVIDER: S-EPMC4940905 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature