Cholesterol consumption and risk of endometrial cancer: a systematic review and dose-response meta-analysis of observational studies.

ABSTRACT: In vivo and in vitro studies have indicated the link of cholesterol consumption and endometrial cancer risk, however, previous observational studies have yielded inconsistent results. Additionally, a previous meta-analysis published in 2007 found limited evidence of aforementioned association. Therefore, we performed the dose-response meta-analysis to address this concern. Studies were identified using the PubMed, EMBASE and Web of Science databases from the database inception to the end of June 2015 as well as by examining the references of retrieved articles. Two authors independently performed the eligibility evaluation and data extraction. The summary risk estimates and 95% confidence intervals (CIs) were summarized by the random-effects models. One cohort and nine case-control studies

SUBMITTER: Gong TT 

PROVIDER: S-EPMC4941366 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature