Ontology highlight
ABSTRACT:
SUBMITTER: Driessen RP
PROVIDER: S-EPMC4941522 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Scientific reports 20160711
Sso10a proteins are small DNA-binding proteins expressed by the crenarchaeal model organism Sulfolobus solfataricus. Based on the structure of Sso10a1, which contains a winged helix-turn-helix motif, it is believed that Sso10a proteins function as sequence-specific transcription factors. Here we show that Sso10a1 and Sso10a2 exhibit different distinct DNA-binding modes. While the ability to bend DNA is shared between the two proteins, DNA bridging is observed only for Sso10a1 and only Sso10a2 ex ...[more]