A plant-based system for rapid production of influenza vaccine antigens.

ABSTRACT:

Background

Influenza virus is a globally important respiratory pathogen that causes a high degree of annual morbidity and mortality. Significant antigenic drift results in emergence of new, potentially pandemic, virus variants. The best prophylactic option for controlling emerging virus strains is to manufacture and administer pandemic vaccines in sufficient quantities and to do so in a timely manner without impacting the regular seasonal influenza vaccine capacity. Current, egg-based, influenza vaccine production is well established and provides an effective product, but has limited capacity and speed.

Objectives

To satisfy the additional global demand for emerging influenza vaccines, high-performance cost-effective technologies need to be developed. Plants have a potential

SUBMITTER: Shoji Y 

PROVIDER: S-EPMC4941669 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature