Avian influenza A (H5N1) infection in a patient in China, 2006.

ABSTRACT:

Background

Highly pathogenic avian influenza H5N1 virus has caused increasing human infection in Eurasia since 2004. So far, H5N1 human infection has been associated with over 50% mortality that is partly because of delay of diagnosis and treatment.

Objectives and methods

Here, we report that an H5N1 influenza virus infected a 31-year-old patient in Shenzhen in June 2006. To identify the possible source of the infection, the human isolate and other H5N1 influenza viruses obtained from poultry and wild birds in southern China during the same period of time were characterized.

Results

Genetic and antigenic analyses revealed that the human H5N1 influenza virus, Shenzhen/406H/06, is of purely avian origin and is most closely related to viruses detected in poultry and wild

SUBMITTER: Chen X 

PROVIDER: S-EPMC4941883 | biostudies-literature | 2007 Sep-Nov

REPOSITORIES: biostudies-literature