Respiratory syncytial virus infection in infants in rural Nepal.

ABSTRACT:

Objectives

Respiratory syncytial virus (RSV) pneumonia is a leading cause of infant mortality worldwide. The risk of RSV infection associated with preterm birth is not well-characterized in resource-limited settings. We aimed to obtain precise estimates of risk factors and disease burden of RSV in infants in rural southern Nepal.

Methods

Pregnant women were enrolled, and along with their infants, followed to six months after birth with active weekly home-based surveillance for acute respiratory illness (ARI). Mid-nasal swabs were obtained and tested for RSV by PCR for all illness episodes. Birth outcomes were assessed at a postpartum home visit.

Results

311 (9%) of 3509 infants had an RSV ARI. RSV ARI incidence decreased from 551/1000 person-years in infants born betw

SUBMITTER: Chu HY 

PROVIDER: S-EPMC4942356 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature