Comparative Transcriptome Reconstruction of Four Hypericum Species Focused on Hypericin Biosynthesis.

ABSTRACT: Next generation sequencing technology rapidly developed research applications in the field of plant functional genomics. Several Hypericum spp. with an aim to generate and enhance gene annotations especially for genes coding the enzymes supposedly included in biosynthesis of valuable bioactive compounds were analyzed. The first de novo transcriptome profiling of Hypericum annulatum Moris, H. tomentosum L., H. kalmianum L., and H. androsaemum L. leaves cultivated in vitro was accomplished. All four species with only limited genomic information were selected on the basis of differences in ability to synthesize hypericins and presence of dark nodules accumulating these metabolites with purpose to enrich genomic background of Hypericum spp. H. annulatum was chosen because of high number of the

SUBMITTER: Sotak M 

PROVIDER: S-EPMC4942478 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature