A highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutase.

ABSTRACT: Copper/zinc superoxide dismutase (Cu/Zn SOD) is an essential enzyme that protects tissue from oxidative damage. Herein we report the first fluorogenic probe (SODO) for the detection and in vivo imaging of Cu/Zn SOD. SODO represents a unique chemical probe for translational imaging studies of Cu/Zn SOD in inflammatory disorders.

SUBMITTER: Zhang L 

PROVIDER: S-EPMC4943070 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature