Progress in Treatment of Viral Infections in Children with Acute Lymphoblastic Leukemia.

ABSTRACT: In children, the most commonly encountered type of leukemia is acute lymphoblastic leukemia (ALL). An important source of morbidity and mortality in ALL are viral infections. Even though allogeneic transplantations, which are often applied also in ALL, carry a recognized risk for viral infections, there are multiple factors that make ALL patients susceptible to viral infections. The presence of those factors has an influence in the type and severity of infections. Currently available treatment options do not guarantee a positive outcome for every case of viral infection in ALL, without significant side effects. Side effects can have very serious consequences for the ALL patients, which include nephrotoxicity. For this reason a number of strategies for personalized intervention have been al

SUBMITTER: Moschovi M 

PROVIDER: S-EPMC4943096 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature