Cost of Illness of Multiple Sclerosis - A Systematic Review.

ABSTRACT:

Background

Cost-of-illness (COI) studies of Multiple Sclerosis (MS) are vital components for describing the economic burden of MS, and are frequently used in model studies of interventions of MS. We conducted a systematic review of studies estimating the COI of MS, to compare costs between studies and examine cost drivers, emphasizing generalizability and methodological choices.

Material and method

A literature search on studies published in English on COI of MS was performed in PubMed for the period January 1969 to January 2014, resulting in 1,326 publications. A mapping of studies using a bottom-up approach or top-down approach, respectively, was conducted for the 48 studies assessed as relevant. In a second analysis, the cost estimates were compared between the 29 studies

SUBMITTER: Ernstsson O 

PROVIDER: S-EPMC4943600 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature