Exercise duration-matched interval and continuous sprint cycling induce similar increases in AMPK phosphorylation, PGC-1α and VEGF mRNA expression in trained individuals.

ABSTRACT:

Purpose

The effects of low-volume interval and continuous 'all-out' cycling, matched for total exercise duration, on mitochondrial and angiogenic cell signalling was investigated in trained individuals.

Methods

In a repeated measures design, 8 trained males ([Formula: see text], 57 ± 7 ml kg(-1) min(-1)) performed two cycling exercise protocols; interval (INT, 4 × 30 s maximal sprints interspersed by 4 min passive recovery) or continuous (CON, 2 min continuous maximal sprint). Muscle biopsies were obtained before, immediately after and 3 h post-exercise.

Results

Total work was 53 % greater (P = 0.01) in INT compared to CON (71.2 ± 7.3 vs. 46.3 ± 2.7 kJ, respectively). Phosphorylation of AMPK(Thr172) increased by a similar magnitude (P = 0.347) immediately post INT and

SUBMITTER: Taylor CW 

PROVIDER: S-EPMC4943987 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature