Midline thalamic neurons are differentially engaged during hippocampus network oscillations.

ABSTRACT: The midline thalamus is reciprocally connected with the medial temporal lobe, where neural circuitry essential for spatial navigation and memory formation resides. Yet, little information is available on the dynamic relationship between activity patterns in the midline thalamus and medial temporal lobe. Here, we report on the functional heterogeneity of anatomically-identified thalamic neurons and the differential modulation of their activity with respect to dorsal hippocampal rhythms in the anesthetized mouse. Midline thalamic neurons expressing the calcium-binding protein calretinin, irrespective of their selective co-expression of calbindin, discharged at overall low levels, did not increase their activity during hippocampal theta oscillations, and their firing rates were inhibited duri

SUBMITTER: Lara-Vasquez A 

PROVIDER: S-EPMC4944155 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature