High Mortality in Severe Sepsis and Septic Shock Patients with Do-Not-Resuscitate Orders in East Asia.

ABSTRACT:

Background

Severe sepsis is a potentially deadly illness and always requires intensive care. Do-not-resuscitate (DNR) orders remain a debated issue in critical care and limited data exist about its impact on care of septic patients, particularly in East Asia. We sought to assess outcome of severe sepsis patients with regard to DNR status in Taiwan.

Methods

A retrospective cohort study was conducted in intensive care units (ICUs) between 2008 and 2010. All severe sepsis patients were included for analysis. Primary outcome was association between DNR orders and ICU mortality. Volume of interventions was used as proxy indicator to indicate aggressiveness of care.

Results

Sixty-seven (9.4%) of 712 patients had DNR orders on ICU admission, and these patients were older and

SUBMITTER: Huang CT 

PROVIDER: S-EPMC4944975 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature