Sleep and Cognitive Function in Multiple Sclerosis.

ABSTRACT:

Study objectives

To examine associations between cognitive performance and polysomnographic measures of obstructive sleep apnea in patients with multiple sclerosis (MS).

Methods

Participants underwent a comprehensive MS-specific cognitive testing battery (the Minimal Assessment of Cognitive Function in MS, or MACFIMS) and in-laboratory overnight PSG.

Results

In adjusted linear regression models, the oxygen desaturation index (ODI) and minimum oxygen saturation (MinO2) were significantly associated with performance on multiple MACFIMS measures, including the Paced Auditory Serial Addition Test (PASAT; 2-sec and 3-sec versions), which assesses working memory, processing speed, and attention, and on the Brief Visuospatial Memory Test-Revised, a test of delayed visual mem

SUBMITTER: Braley TJ 

PROVIDER: S-EPMC4945311 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature