Spectral and spatial changes of brain rhythmic activity in response to the sustained thermal pain stimulation.

ABSTRACT: The aim of this study was to investigate the neurophysiological correlates of pain caused by sustained thermal stimulation. A group of 21 healthy volunteers was studied. Sixty-four channel continuous electroencephalography (EEG) was recorded while the subject received tonic thermal stimulation. Spectral changes extracted from EEG were quantified and correlated with pain scales reported by subjects, the stimulation intensity, and the time course. Network connectivity was assessed to study the changes in connectivity patterns and strengths among brain regions that have been previously implicated in pain processing. Spectrally, a global reduction in power was observed in the lower spectral range, from delta to alpha, with the most marked changes in the alpha band. Spatially, the contralateral

SUBMITTER: Huishi Zhang C 

PROVIDER: S-EPMC4945371 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature