DNA-catalyzed glycosylation using aryl glycoside donors.

ABSTRACT: We report the identification by in vitro selection of Zn(2+)/Mn(2+)-dependent deoxyribozymes that glycosylate the 3'-OH of a DNA oligonucleotide. Both β and α anomers of aryl glycosides can be used as the glycosyl donors. Individual deoxyribozymes are each specific for a particular donor anomer.

SUBMITTER: Hesser AR 

PROVIDER: S-EPMC4945402 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature