A surface-based technique for mapping homotopic interhemispheric connectivity: Development, characterization, and clinical application.

ABSTRACT: The functional organization of the human brain consists of a high degree of connectivity between interhemispheric homologous regions. The degree of homotopic organization is known to vary across the cortex and homotopic connectivity is high in regions that share cross-hemisphere structural connections or are activated by common input streams (e.g., the visual system). Damage to one or both regions, as well as damage to the connections between homotopic regions, could disrupt this functional organization. Here were introduce and test a computationally efficient technique, surface-based homotopic interhermispheric connectivity (sHIC), that leverages surface-based registration and processing techniques in an attempt to improve the spatial specificity and accuracy of cortical interhemispheric

SUBMITTER: Tobyne SM 

PROVIDER: S-EPMC4945467 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature