Plasma dipeptidyl peptidase IV activity and measures of body composition in apparently healthy people.

ABSTRACT:

Aim

Based on its regulatory action on glucagon-like peptide 1, dipeptidyl peptidase IV (DPP-IV) has increasingly been linked to Type 2 diabetes. However, there is no evidence as to how this normal modulatory enzyme leads to pathology. It is thought that DPP-IV is affected by the development of obesity, which is a common precursor to Type 2 diabetes. Little is known about the relationship between DPP-IV activity in plasma and specific body composition measures.

Main methods

In the current study, plasma DPP-IV activity and body composition measures were collected from 111 healthy subjects between the ages of 19 and 70 years old for analysis.

Key findings

The mean plasma DPP-IV activity was 35.9U/L ± 12.3, falling within normal reference value range presented by Durinx e

SUBMITTER: Neidert LE 

PROVIDER: S-EPMC4946079 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature