Ontology highlight
ABSTRACT:
SUBMITTER: Toselli-Mollereau E
PROVIDER: S-EPMC4946138 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Toselli-Mollereau Esther E Robellet Xavier X Fauque Lydia L Lemaire Sébastien S Schiklenk Christoph C Klein Carlo C Hocquet Clémence C Legros Pénélope P N'Guyen Lia L Mouillard Léo L Chautard Emilie E Auboeuf Didier D Haering Christian H CH Bernard Pascal P
The EMBO journal 20160606 14
Condensins associate with DNA and shape mitotic chromosomes. Condensins are enriched nearby highly expressed genes during mitosis, but how this binding is achieved and what features associated with transcription attract condensins remain unclear. Here, we report that condensin accumulates at or in the immediate vicinity of nucleosome-depleted regions during fission yeast mitosis. Two transcriptional coactivators, the Gcn5 histone acetyltransferase and the RSC chromatin-remodelling complex, bind ...[more]