Smoking Status Influences Clinical Outcome in Collagenous Colitis.

ABSTRACT:

Background

The relationship between clinical and histological parameters in collagenous colitis (CC) is poorly understood. Smoking is a risk factor for CC, whereas its impact on clinical activity and outcome is not well known.

Methods

In a post hoc analysis of pooled data from two randomized controlled trials we assessed the association between demographic data (gender, age, smoking habits, family history of inflammatory bowel disease), clinical variables (duration of symptoms, mean number of stools/watery stools per day, abdominal pain, clinical remission) and histological data (thickness of the collagen band, inflammation of the lamina propria, total numbers of intraepithelial lymphocytes, degeneration). Moreover, we analysed the predictive value of baseline parameters for

SUBMITTER: Munch A 

PROVIDER: S-EPMC4946766 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature