Quantitative Susceptibility Mapping in Cerebral Cavernous Malformations: Clinical Correlations.

ABSTRACT:

Background and purpose

Quantitative susceptibility mapping has been shown to assess iron content in cerebral cavernous malformations. In this study, our aim was to correlate lesional iron deposition assessed by quantitative susceptibility mapping with clinical and disease features in patients with cerebral cavernous malformations.

Materials and methods

Patients underwent routine clinical scans in addition to quantitative susceptibility mapping on 3T systems. Data from 105 patients met the inclusion criteria. Cerebral cavernous malformation lesions identified on susceptibility maps were cross-verified by T2-weighted images and differentiated on the basis of prior overt hemorrhage. Mean susceptibility per cerebral cavernous malformation lesion (χ̄lesion) was measured to correl

SUBMITTER: Tan H 

PROVIDER: S-EPMC4947004 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature