A Recent Whole-Genome Duplication Divides Populations of a Globally Distributed Microsporidian.

ABSTRACT: The Microsporidia are a major group of intracellular fungi and important parasites of animals including insects, fish, and immunocompromised humans. Microsporidian genomes have undergone extreme reductive evolution but there are major differences in genome size and structure within the group: some are prokaryote-like in size and organisation (<3 Mb of gene-dense sequence) while others have more typically eukaryotic genome architectures. To gain fine-scale, population-level insight into the evolutionary dynamics of these tiny eukaryotic genomes, we performed the broadest microsporidian population genomic study to date, sequencing geographically isolated strains of Spraguea, a marine microsporidian infecting goosefish worldwide. Our analysis revealed that population structure across the Atla

SUBMITTER: Williams TA 

PROVIDER: S-EPMC4948709 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature