The Effect of Start and Stop Age at Screening on the Risk of Being Diagnosed with Prostate Cancer.

ABSTRACT:

Purpose

We investigated the effect of age and number of screens on the risk of prostate cancer diagnosis.

Materials and methods

Since 1995 the Göteborg randomized population based prostate cancer screening trial has invited men biennially for prostate specific antigen testing, until the upper age limit of 70 years. Men with a prostate specific antigen above the threshold of 2.5 ng/ml were recommended further evaluation including 10-core biopsy (sextant before 2009). The present study comprises 9,065 men born between 1930 and 1943 (1944 excluded due to different screening algorithm). Complete attendees were defined as men who accepted all screening invitations (maximum 3 to 9 invitations). The cumulative incidence of prostate cancer was calculated using standard methods.

R

SUBMITTER: Godtman RA 

PROVIDER: S-EPMC4948858 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature