Interactive cost of Plasmodium infection and insecticide resistance in the malaria vector Anopheles gambiae.

ABSTRACT: Insecticide resistance raises concerns for the control of vector-borne diseases. However, its impact on parasite transmission could be diverse when considering the ecological interactions between vector and parasite. Thus we investigated the fitness cost associated with insecticide resistance and Plasmodium falciparum infection as well as their interactive cost on Anopheles gambiae survival and fecundity. In absence of infection, we observed a cost on fecundity associated with insecticide resistance. However, survival was higher for mosquito bearing the kdr mutation and equal for those with the ace-1(R) mutation compared to their insecticide susceptible counterparts. Interestingly, Plasmodium infection reduced survival only in the insecticide resistant strains but not in the susceptible on

SUBMITTER: Alout H 

PROVIDER: S-EPMC4949420 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature