Arsenic-Containing Phosphatidylcholines: A New Group of Arsenolipids Discovered in Herring Caviar.

ABSTRACT: A new group of arsenolipids based on cell-membrane phosphatidylcholines has been discovered in herring caviar (fish roe). A combination of HPLC with elemental and molecular mass spectrometry was used to identify five arsenic-containing phosphatidylcholines; the same technique applied to salmon caviar identified an arsenic-containing phosphatidylethanolamine. The arsenic group in these membrane lipids might impart particular properties to the molecules not displayed by their non-arsenic analogues. Additionally, the new compounds have human health implications according to recent results showing high cytotoxicity for some arsenolipids.

SUBMITTER: Viczek SA 

PROVIDER: S-EPMC4949577 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature