Do early-life exposures explain why more advantaged children get eczema? Findings from the U.K. Millennium Cohort Study.

ABSTRACT:

Background

Atopic dermatitis (eczema) in childhood is socially patterned, with higher incidence in more advantaged populations. However, it is unclear what factors explain the social differences.

Objectives

To identify early-life risk factors for eczema, and to explore how early-life risk factors explain any differences in eczema.

Methods

We estimated odds ratios (ORs) for ever having had eczema by age 5 years in 14 499 children from the U.K. Millennium Cohort Study (MCS), with a focus on maternal, antenatal and early-life risk factors and socioeconomic circumstances (SECs). Risk factors were explored to assess whether they attenuated associations between SECs and eczema.

Results

Overall 35·1% of children had ever had eczema by age 5 years. Children of mothers

SUBMITTER: Taylor-Robinson DC 

PROVIDER: S-EPMC4949701 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature