Cellular mechanisms for cargo delivery and polarity maintenance at different polar domains in plant cells.

ABSTRACT: The asymmetric localization of proteins in the plasma membrane domains of eukaryotic cells is a fundamental manifestation of cell polarity that is central to multicellular organization and developmental patterning. In plants, the mechanisms underlying the polar localization of cargo proteins are still largely unknown and appear to be fundamentally distinct from those operating in mammals. Here, we present a systematic, quantitative comparative analysis of the polar delivery and subcellular localization of proteins that characterize distinct polar plasma membrane domains in plant cells. The combination of microscopic analyses and computational modeling revealed a mechanistic framework common to diverse polar cargos and underlying the establishment and maintenance of apical, basal, and later

SUBMITTER: Langowski L 

PROVIDER: S-EPMC4950145 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature